Research

Publications – 2010

Ellsworth RE, Decewicz DJ, Shriver CD, Ellsworth DL. "Breast Cancer in the Personal Genomics Era" Current Genomics, 2010; 11:146-161.

Ellsworth RE, Ellsworth DL, Weyandt JD, Fantacone-Campbell JL, Deyarmin B, Hooke JA, Shriver CD. "Chromosomal Alterations in Pure Breast Lesions: Implications for Breast Cancer Progression" AnnSurgOncol, 27 Jan 2010. PMID: 20107913 [PubMed]

Stojadinovic A, Eberhardt C, Henry L, Eberhardt J, Elster E, Peoples G, Nissan A, Shriver C. "Development of a Bayesian Classifier for Breast Cancer Risk Stratification: A Feasibility Study" Eplasty, vol 10, pp 203-216, 29 Mar 10, ISSN: 1937-5719. Open Science Co. LLC, Springfield, IL.

Buckenmaier III CC, Kwon KH, Howard RS, McKnight GM, Shriver CD, Fritz WT, Garguilo GA, Joltes KH, Stojadinovic A. "Double-Blinded, Placebo Controlled Prospective Randomized Trial Evaluating the Efficacy of Paravertebral Block With and Without Continuous Paravertebral Block Analgesia in Outpatient Breast Cancer Surgery" Pain Medicine 2010; 11:790-799. Wiley Periodicals, Inc.

Abstracts – 2010

Ellsworth RE, Oviedo AL, Kane JL, Shriver CD. "Breastfeeding, Baby Boomers and Breast Cancer" Society of Surgical Oncology (SSO) Mar 2011. San Antonio, Texas

Ellsworth RE, Field LA, Love B, Kane JL, Hooke JA, Shriver CD. "Breast cancer metastasis gene signature: the search for the Holy Grail." Personalized Cancer Therapy & Prevention, 8-9 Oct 2010, Houston, Texas

Field L, Rummel S, Shriver CD, Ellsworth RE. "The role of PSPHL in breast cancer in African American women." SABCS 8-12 Dec 2010, San Antonio, Texas

Saini J, Li X, Kvecher L, Larson C, Croft D, Yang Y, Hooke JA, Shriver CD, Mural RJ, Hu H. "Differential Gene Expression Analysis among Post-menopausal Caucasian Invasive Breast Cancer, Benign and Normal Subjects." SABCS 8-12 Dec 2010, San Antonio, Texas

Kopco R, Iida J, Lehman J, Somiari S, Somiari R, Mural R, Shriver C. "Development of DNA aptamers that inhibit invasion, migration, and growth of breast cancer Cells." SABCS 8-12 Dec 2010, San Antonio, Texas

Zhou J, Somiari S, Lubert S, Saini J, Hooke J, Mural R, Shriver C, Brinckerhoff C. " The Impact of Matrix Metalloproteinase-1 Promoter 1G/2G Polymorphism on Breast Diseases." SABCS 8-12 Dec 2010, San Antonio, Texas

Rapuri PB, Li X, Brilhart G, Deyarmin B, Kvecher L, Hu H, Hooke J, Shriver C, Mural R. "Comparison of gene expression profiles of lymph node metastatic and non-metastatic ER+ve breast tumors in pre and post menopausal women." SABCS 8-12 Dec 2010, San Antonio, Texas

Bekhash A, Saini J, Li X, Rapuri P, Hooke JA, Kovatich A, Mural RJ, Shriver CD, Hu H. "Ethnicity Difference of Benign Breast Diseases in Breast Cancer and Non-Cancer Patients." SABCS 8-12 Dec 2010, San Antonio, Texas

Ellsworth RE, Fantacone-Campbell JL, Valente A, Shriver C. "Chromosomal alterations associated with poor outcome in breast cancer patients". SABCS 8-12 Dec 2010, San Antonio, Texas Ellsworth R, Deyarmin B, Patney H, Shriver C, Ellison K, Thornton D, Tafra L, Cheng Z, Rosman M." Genetic discrimination of aggressive from indolent DCIS." SABCS 8-12 Dec 2010, San Antonio, Texas

Ellsworth RE, Patney HL, Kane JA, Hooke JA, Shriver CD. "Role of chromosome 16q in breast tumorigenesis." SABCS 8-12 Dec 2010, San Antonio, Texas

Ellsworth RE, Field LA, Love B, Kane JL, Hooke JA, Shriver CD. "Breast Cancer Metastasis Gene Signature: The Search for the Holy Grail." American Society of Clinical Oncology (ASCO), Jun 2010, Chicago, Illinoisv

Rummel S, Ellsworth RE, Kane J, Deyarmin B, Hooke JA, Ellsworth DL, Shriver CD. "Genomic Instability of Breast Stroma." American Association for Cancer Research (AACR) 17-21 Apr 2010, Washington, DC

Ellsworth RE, Sann NJ, Kvecher L, Ellsworth DL, Shriver CD. "Is a Diagnosis of Invasive Breast Cancer an Effective Motivational Factor for Lifestyle Change?" National Consortium of Breast Centers (NCBC), 20-24 Mar 2010, Las Vegas, Nevada

Ellsworth RE, Ellsworth DL, Weyandt JD, Fantacone-Campbell JL, Deyarmin B, Hooke JA, Shriver CD. "Chromosomal Alterations in Pure Breast Lesions: Implications for Breast Cancer Progression." Society of Surgical Oncology (SSO), 3-7 Mar 2010, St Louis, Missouri

Publications – 2009

Correll M, Beaulah S, Munro R, Sheldon J, Guo Y, Hu H. “Data Mining Tools and Techniques for Identification of Biomarkers for Cancer.” Jake Chen and Stefano Lonardi (Editors). Biological Data Mining. Chapman and Hall/CRC. Book Chapter. In press 2009.

Ellsworth RE, Hooke JA, Shriver CD, Ellsworth DL. “Genomic Heterogeneity of Breast Tumor Pathogenesis“. ClinMedOnc 2009;3;77-85

Holliday C, Rummel S, Hooke JA, Shriver CD, Ellsworth DL, Ellsworth RE. “Genomic Instability in the Breast Microenvironment? A Critical Evaluation of the Evidence”. Expert Reviews in Molecular Diagnosis Journal. In press

Bronfman L, Shriver CD. “A New Paradigm for Integrating Translational Research into Comprehensive Breast Care: The Walter Reed Army Medical Center / Windber Research Institute Experience”. Seminars in Breast Disease Journal. In press.

Field LA, Love B, Kane J, Deyarmin B, Hooke JA, Ellsworth RE, Shriver CD. “Gene Expression Differences in Normal Breast Tissue from Disease-Free African American and Caucasian Women”. Breast Cancer Research Journal, BioMed Central Ltd, Middlesex House, London, UK, Jan 09

Abstracts – 2009

Ellsworth RE, Field LA, Hooke JA, Kane JA, Love BL, Shriver CD. “Identification of a Molecular Signature of Breast Cancer Metastasis”. SABCS 9-13 Dec 09, San Antonio, TX

Ellsworth RE, Deyarmin B, Hooke JA, Shriver CD. “Clinical Implications of The Molecular Relationship Between HER2 and BRCA1”. SABCS 9-13 Dec 09, San Antonio, TX

Li X, Hu H, Shriver CD, Mural, RJ. “High-throughput Microarray Data Analysis Using Blood Samples in Human Breast Cancer Study”. SABCS 9-13 Dec 09, San Antonio, TX

Bekhash A, Saini J, Yu Fan X, Hooke JA, Mural RJ, Shriver CD, Hu H. “Differential Benign Breast Disease Co-occurrence with Cancer in Caucasian and African American Women”. SABCS 9-13 Dec 09, San Antonio, TX

Saini J, Kovatich A, Li X, Bekash A, Hooke JA, Mural R, Shriver CD, Hu H. “Association of Clinicopathologic Characteristics with IHC-Based Breast Cancer Subtypes”. SABCS 9-13 Dec 09, San Antonio, TX

Kvecher L, Wu V, Hooke JA, Shriver CD, Mural RJ, Hu H. “An Approach to Correlate the Temporal Information to Facilitate Specimen Selection in the Breast Cancer Research Project”. SABCS 9-13 Dec 09, San Antonio, TX

Shay M, Duman J, Christiansen R, Eberly S, Hu H, Shriver CD. “Converting Paper Medical Records to Electronic Version to Support Breast Cancer Translational Research and Clinical Practice”. SABCS 9-13 Dec 09, San Antonio, TX

Iida J, Nesbella M, Lehman J, Mural R, Shriver CD. “Role for CD44 in Enhancing Invasion, Migration, and Growth of Triple negative (TN) Breast Cancer Cells”. SABCS 9-13 Dec 09, San Antonio, TX

Sann NJ, Ellsworth RE, Kvecher L, Shriver CD, Ellsworth DL. “Is a Diagnosis of Invasive Breast Cancer an Effective motivational factor for lifestyle change?” Society of Surgical Oncology, 5-9 Mar 09, Phoenix, AZ

Ellsworth RE, Becker TE, Progar C, Deyarmin B, Shriver CD. “Characterization of Screen Versus Non-Screen Detected Breast Tumors”. Society of Surgical Oncology, 5-9 Mar 09, Phoenix, AZ

Ellsworth RE, Weyandt JD, Fantacone-Campbell JL, Deyarmin B, Ellsworth DL, Hooke JL, Shriver CD. “Genetic Characterization of Columnar Cellular Lesions and Atypical Ductal Hyperplasia of the Breast”. SABCS 9-13 Dec 09, San Antonio, TX

Ellsworth RE, Seeley EH, Ellsworth EL, Deyarmin B, Hooke JA, Sanders M, Caprioli R, Shriver CD. “Proteomic Discrimination of Well- from poorly-Differentiated Breast Carcinomas.” SABCS Dec 09, San Antonio, TX

Patney HL, Kane JL, Weyandt J, Hooke JA, Shriver CD, Ellsworth RE. “Copy Number Variation in Low- and High-Grade Breast Tumors”. ASHG, 20-24 Oct 09, Honolulu, Hawaii.

Iida J, Nesbella M, Lehman J, Mural R, Shriver CD. “Role for CD44 in Enhancing Invasion, Migration, and Growth of Triple Negative (TN) Breast Cancer Cells.” Circulating Tumor Cells: Emerging Technologies for Detection, Diagnostics and Treatment, NIH, 10-11 Sep 09, Bethesda, MD.

Weyandt J, Ellsworth RE, Hooke JA, Shriver CD, Ellsworth DL. “Molecular Characteristics of Early Breast Disease”. AACR, 18-22 Apr 2009, Denver, CO

Ellsworth RE, Weyandt JM, Fantacone-Campbell JL, Deyarmin B, Ellsworth DL, Hooke JA, Shriver CD. “Molecular Characterization of Breast Cancer Progression: Early Lesions are not Genetically Advanced”. AACR 18-22 Apr 09 Denver, CO

Publications – 2008

Maskery SM, Hu H, Hooke J, Shriver CD, Liebman MN. "A Bayesian Derived Network of Breast Pathology Co-Occurrence". Journal of Biomedical Informatics. In print 2008

Ellsworth RA, Ellsworth DL, Patney HL, Love B, Deyarmin B, Hooke JA, Shriver CD. “Genomic Alterations Associated with Early Stages of Breast Tumor Metastasis.” AnnSurgOncol, DOI:10.1245/s10434-008-9902-5.

Becker TE, Ellsworth RE, Deyarmin B, Patney HL, Jordan RM, Hooke JA, Shriver CD. Ellsworth DL. “Genomic Heritage of Lymph Node Metastases: Implications for Clinical Management of Patients with Breast Cancer.” Clinical Biochemistry Journal, Mar 08 submitted

Weyandt J, Ellsworth RE, Hooke JA, Shriver CD, Ellsworth DL. “Environmental Chemicals and Breast Cancer Risk – A Structural Chemistry Perspective”. Current Medicinal Chemistry, 2008, 15, 2680-2701.

Callaghan KA, Ellsworth RL, Ellsworth DL, Shriver CD. “HER2 in the Era of Molecular Medicine: A Review”. Current Cancer Therapy Reviews, 2008, 4, 00-00. 1573-3947/08. Bentham Science Publishers Ltd.

Croft DT Jr, Jordan RM, Patney HL, Shriver CD, Vernalis MN, Orchard TJ, Ellsworth DL. “Performance of Whole-Genome Amplified DNA Isolated from Serum and Plasma on High Density Single Nucleotide Polymorphism Arrays”. JMolDiagn; 10(3):249-57. May 2008. DOI: 10.2353/jmoldx.2008.070155.

Ellsworth RE, Ellsworth DL, Patney HL, Deyarmin B, Love B, Hooke J, Shriver CD. “Amplication of HER2 is a Marker for Global Genomic Instability”. BioMed Central Ltd. BMC Cancer 2008 Oct 14; 8:297. DOI: 10.1186/1471-2407-8-297

Presentations – 2008

Ellsworth RA, Patney HL, Ellsworth DL, Love B, Deyarmin B, Hooke JA, Shriver CD. “Genomic Alterations Associated with Early Stages of Breast Tumor Metastasis.” Society of Surgical Oncology, May 2008, Chicago, IL

Ellsworth DL, Ellsworth RE, Patney HL, Becker TE, Deyarmin B, Hooke JA, Shriver CD. “Molecular Heterogeneity Among Sentinel Lymph Node Metastases: Implications for the Sentinel Node Hypothesis.” Breast Cancer Symposium 5-7 Sep 08, Washington, DC

Abstracts – 2008

Patney HL, Deyarmin B, Hooke JA, Ellsworth RE, Love B, Shriver CD. “Relationship Between Alterations of Chromosome 8q24 and Poorly-Differentiated Breast Carcinoma”. SABCS 10-14 Dec 08, San Antonio, TX

Ellsworth RE, Heckman C, Love B, Shriver CD. “Identification of Breast Cancer Metastasis Initiation and Virulence Genes”. SABCS 10-14 Dec 08, San Antonio, TX

Field LA, Love BJ, Kane J, Deyarmin B, Hooke JA, Ellsworth RE, Shriver CD. “Role of Phosphoserine Phosphatase-like in Breast Disease in African American Women”. SABCS 10-14 Dec 08, San Antonio, TX

Ellsworth DL, Ellsworth RL, Patney HL, Oviedo A, George A, Croft, DT, Jr., Love B, Jordan RM, Deyarmin B, Becker TE, Hooke JA, Shriver CD. “Fingerprinting Genomic Heterogeneity in Primary Breast Carcinomas and Among Sentinel Lymph Node Metastases: Implications for Clinical Management of Breast Cancer Patients”. SABCS 10-14 Dec 08, San Antonio, TX

Ellsworth DL, Gillard D, Love B, Ellsworth RE, Deyarmin B, Hooke JA, Kostyniak PJ, Shriver CD. “Abundance and Distribution of Polychlorinated Biphenyls (PCBs) in Breast Tissue”. SABCS 10-14 Dec 08, San Antonio, TX

Croft D, Mao X, Hooke JA, Shriver CD, Shriver M, Ellsworth RE. “Admixture Mapping to Identify Breast Cancer Susceptibility Loci in African American Women”. SABCS 10-14 Dec 08, San Antonio, TX

Patney HL, Deyarmin B, Hooke JA, Ellsworth RE, Love B, Shriver CD. “Relationship Between Alterations of Chromosome 8q24 and Poorly-Differentiated Breast Carcinoma.” SABCS 10-14 Dec 08, San Antonio, TX

Ellsworth RE, Heckman C, Love B, Shriver CD. “Identification of Breast Cancer Metastasis Initiation and Virulence Genes”. SABCS 10-14 Dec 08, San Antonio, TX

Shriver CD. “Star Wars Defense Battles Breast Cancer.” Press Release Conjoint Royal Australasian College of Surgeons and the College of Surgeons of Hong Kong, May 08

Shriver CD. “Well-documented Breast Cancer Tissue Collection Meets High Throughout Proteomics to Find Aggressive-tumor Markers in Blood.” Press Release, PNNL, May 08

Shoemaker A, Heckman C, Zhang Y, Colledge A, Deyarmin B, Kane J, Hooke J, Shriver C, Mural R, Somiari S. “RNA Quality of Human Breast Tissue after Surgical Removal-Effect of Processing Method, Temperature and Storage.” ISBER, Bethesda, MD, May 18-21, 2008

Fields L. “Gene Expression Differences in Primary Breast Tumors from African American and Caucasian women.” AACR 12-16 Apr 08 San Diego, CA

Somiari SB, Kovatich AJ, Zhang Y , Baran PN, Deyarmin B, Kane J, Hooke J, Mural R, Shriver CD. “The Prognostic Role of Cell Cycle Regulators in Invasive Breast Cancer.” AACR April 12-16th, 2008 San Diego, CA

Shoemaker A, Heckman C, Zhang Y, Colledge A, Deyarmin B, Kane J, Hooke J, Shriver C, Mural R, Somiari S. “The Prognostic Role of Cell Cycle Regulators in Invasive Breast Cancer.” AACR, April 12-16th, 2008 San Diego, CA

Ellsworth RE, Hooke JA, Shriver CD. “Effect of Equal-Access to Breast Care on Clinicopathological Phenotypes of Invasive Breast Tumors in African American”. AACR, 12-16 Apr 08, San Diego, CA

Stojadinovic A. “Assessment of Circulating of Tumor Cells (CTCs) for Monitoring Immediate and Long-Term Response to Primary and Booster Inoculations with a Preventative HER2/neu Vaccine in Breast Cancer Patients.” American Association for Cancer Research (AACR) 12-16 Apr 08, San Diego, California

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