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Research

Biospecimen Repository

COL Craig Shriver, Director and Principal Investigator of the Clinical Breast Care Project outside of tissue freezers, visible as one enters the Windber Research Institute.

CBCP has the world’s largest biorepository from breast patients of human breast tissues, lymph nodes, sentinel nodes, sera, bone marrow aspirates, cancers, benign tumors, pre-malignant disease, and other biospecimens, now numbering over 35,000 specimens (contributed by over 4,000 patients) as of October 2009. This unique resource is tapped for both internal (CBCP and WRI) scientific research in the general realms of genomic and proteomic research, as well as for targeted collaborations with extramural collaborators from academia, governmental organizations, and corporate entities, in order to fully leverage the power of this unique international resource.

COL Craig Shriver, Director and Principal Investigator of the Clinical Breast Care Project with Jim Bombatch, Tissue Bank Manger in the freezer area, visible as one enters the Windber Research Institute.

CBCP’s biorepository is unique in that it is powerfully characterized by clinical, demographic, and pathologic information gleaned from its originating patients through robust IRB-approved and fully HIPPA-compliant protocols that exceed all existing regulatory requirements for patient consent, privacy, and oversight.

CBCP has one of the few fully integrated genomic and proteomic molecular biology research programs in the nation devoted exclusively to research in breast diseases. We have an established track record of publication and scientific communication in this field, to include publication in THE LANCET Oncology in December 2004 on our unique discovery of genomic changes in pathologically non-neoplastic breast tissues.

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